Hugo Drax (Moonraker, 1979)
Drax may be your bog-standard villainous megalomaniac, but he wins a place on this list simply for plotting the most grandiose scheme of any Bond villain. Not for him the piffling crimes of irradiating Fort Knox or drug smuggling, no - he wants to destroy all life on earth and repopulate it with his army of gym bunnies. From his secret base. In spaaaaaace. Well, no-one can accuse him of not thinking big.